【summary】
Cancer survivors are at increased risk of fragility fractures, but accurate evaluation has been challenging because many previous studies did not consider the timing of cancer diagnosis. In this 10-year cohort study of 10,330 Japanese adults, researchers found that cancer survivors had a 40% higher risk of fragility fractures than individuals without cancer. The risk was especially high among patients with active cancer, multiple primary cancers, and gastric, kidney, or hematologic cancers. By applying a time-dependent Cox proportional hazards model, the study provides a more accurate assessment of fracture risk and supports the importance of bone health management in cancer survivorship.